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1237168-58-9

1237168-58-9 Structure

1237168-58-9 Structure
IdentificationBack Directory
[Name]

2(3H)-Benzoxazolone, 5-[[2-[(4-fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4-pyrimidinyl]amino]-3-[(phosphonooxy)methyl]-
[CAS]

1237168-58-9
[Synonyms]

Fosifidancitinib
Janus kinase,JAK,Inhibitor,Fosifidancitinib,inhibit
2(3H)-Benzoxazolone, 5-[[2-[(4-fluoro-3-methoxy-5-methylphenyl)amino]-5-methyl-4-pyrimidinyl]amino]-3-[(phosphonooxy)methyl]-
[Molecular Formula]

C21H21FN5O7P
[MDL Number]

MFCD34578235
[MOL File]

1237168-58-9.mol
[Molecular Weight]

505.39
Chemical PropertiesBack Directory
[Boiling point ]

761.3±70.0 °C(Predicted)
[density ]

1.564±0.06 g/cm3(Predicted)
[pka]

1.75±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

Fosifidancitinib is a potent and selective inhibitor of JAK kinases 1/3. Fociatinib is used in studies of allergies, asthma and autoimmune diseases[1].
[References]

[1] Li, Hui; Heckrodt, Thilo J.; Chen, Yan; Mcmurtrie, Darren John; Taylor, Vanessa; Singh, Rajinder; Ding, Pingyu; Yen, Rose.Preparation of phenylaminopyrimidinylaminooxobenzooxazole derivatives for use as JAK kinase inhibitors. WO2012015972A1
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