| Identification | Back Directory | [Name]
Ethanone, 1-(2-amino-4-fluoro-5-methylphenyl)-2-chloro- | [CAS]
1241391-14-9 | [Synonyms]
MC-GGFG-AM-(10Me-11F-Camptothecin) intermediate-1
Ethanone, 1-(2-amino-4-fluoro-5-methylphenyl)-2-chloro- | [Molecular Formula]
C9H9ClFNO | [MOL File]
1241391-14-9.mol | [Molecular Weight]
201.63 |
| Chemical Properties | Back Directory | [Melting point ]
111-113 °C(Solv: hexane (110-54-3)) | [Boiling point ]
333.3±37.0 °C(Predicted) | [density ]
1.299±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
-0.40±0.13(Predicted) | [color ]
Yellow to brown |
| Hazard Information | Back Directory | [Uses]
MC-GGFG-AM-(10Me-11F-Camptothecin) intermediate-1 (compound 19-2) is an intermediate for the synthesis of MC-GGFG-AM-(10Me-11F-Camptothecin) (HY-153360). Modifying groups can be added group. MC-GGFG-AM-(10Me-11F-Camptothecin) is a drug-linker conjugate used in the synthesis of ADCs[1]. | [References]
[1] Jiangsu Simcere Pharmaceutical, et al. Camptothecin derivative, and pharmaceutical composition and use thereof. World Intellectual Property Organization, WO2023020605 A1 2023-02-23. |
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Shanghai URChem Limited
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