ChemicalBook--->CAS DataBase List--->124223-99-0

124223-99-0

124223-99-0 Structure

124223-99-0 Structure
IdentificationBack Directory
[Name]

4-METHYLUMBELLIFERYL 2-ACETAMIDO-2-DEOXY-ALPHA-D-GALACTOPYRANOSIDE
[CAS]

124223-99-0
[Synonyms]

GalNAc1-α-4MU
GalNAc-alpha-4MU
7-[[2-(AcetylaMino)-2-deoxy-α-D-galactopyranosyl]oxy]-4-Methyl-
7-[[2-(Acetylamino)-2-deoxy-a-D-galactopyranosyl]oxy]-4-methyl-2H-1-benzopyran-2-one
[Molecular Formula]

C18H21NO8
[MDL Number]

MFCD00270047
[MOL File]

124223-99-0.mol
Chemical PropertiesBack Directory
[Appearance]

Off-White Solid
[Melting point ]

257-260°C
[storage temp. ]

-20?C Freezer
[solubility ]

DMSO (Slightly), Methanol (Slightly, Heated)
[form ]

Solid
[color ]

White to Off-White
[CAS DataBase Reference]

124223-99-0
Hazard InformationBack Directory
[Chemical Properties]

Off-White Solid
[Uses]

An effective substrate for the detection of N-acetyl-a-D-Galactopyranosiaminidase activity. The deficiency of this enzyme is the defect in Schindler disease
[Uses]

An effective substrate for the detection of N-acetyl-α-D-Galactopyranosiaminidase activity. The deficiency of this enzyme is the defect in Schindler disease.
[Description]

4-Methylumbelliferyl 2-acetoamido-2-deoxy-α-D-galactopyranoside (4-MU-2-acetoamido-2-deoxy-α-Gal) is a fluorogenic substrate used to quantify α- and β-galactopyranosaminidase activity. 4-MU-2-acetoamido-2-deoxy-α-Gal is cleaved by α- and β-galactopyranosaminidase to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases.
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