| Identification | Back Directory | [Name]
4-METHYLUMBELLIFERYL 2-ACETAMIDO-2-DEOXY-ALPHA-D-GALACTOPYRANOSIDE | [CAS]
124223-99-0 | [Synonyms]
GalNAc1-α-4MU
GalNAc-alpha-4MU
7-[[2-(AcetylaMino)-2-deoxy-α-D-galactopyranosyl]oxy]-4-Methyl-
7-[[2-(Acetylamino)-2-deoxy-a-D-galactopyranosyl]oxy]-4-methyl-2H-1-benzopyran-2-one | [Molecular Formula]
C18H21NO8 | [MDL Number]
MFCD00270047 | [MOL File]
124223-99-0.mol | [Molecular Weight]
379.36 |
| Chemical Properties | Back Directory | [Appearance]
Off-White Solid | [Melting point ]
257-260°C | [Boiling point ]
732.2±60.0 °C(Predicted) | [density ]
1.47±0.1 g/cm3(Predicted) | [storage temp. ]
-20?C Freezer | [solubility ]
DMSO (Slightly), Methanol (Slightly, Heated) | [form ]
Solid | [pka]
12.87±0.70(Predicted) | [color ]
White to Off-White | [CAS DataBase Reference]
124223-99-0 |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Solid | [Uses]
An effective substrate for the detection of N-acetyl-a-D-Galactopyranosiaminidase activity. The deficiency of this enzyme is the defect in Schindler disease | [Uses]
An effective substrate for the detection of N-acetyl-α-D-Galactopyranosiaminidase activity. The deficiency of this enzyme is the defect in Schindler disease. | [Description]
4-Methylumbelliferyl 2-acetoamido-2-deoxy-α-D-galactopyranoside (4-MU-2-acetoamido-2-deoxy-α-Gal) is a fluorogenic substrate used to quantify α- and β-galactopyranosaminidase activity. 4-MU-2-acetoamido-2-deoxy-α-Gal is cleaved by α- and β-galactopyranosaminidase to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. | [References]
[1] R. SZWEDA. Synthesis of 4-methylumbelliferyl glycosides for the detection of α- and β-D-galactopyranosaminidases[J]. Canadian Journal of Chemistry, 1989, 22 1: 1388-1391. DOI: 10.1139/v89-213
[2] H. ZHI. Fluorescent properties of hymecromone and fluorimetric analysis of hymecromone in compound dantong capsule[J]. Spectroscopy, 2013, 438 1: 1-9. DOI: 10.1155/2013/147128 |
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Energy Chemical
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021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
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