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124529-64-2

124529-64-2 Structure

124529-64-2 Structure
IdentificationBack Directory
[Name]

tert-Butyl (6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexyl)carbamate
[CAS]

124529-64-2
[Synonyms]

Mal-C4-NH-Boc
Mal-C6-NH-Boc
1-(6-N-Boc-aminohexyl)-1H-pyrrole-2,5-dione
N-[N'-(tert-butyloxycarbonyl)-6-aminohexyl]maleimide
tert-Butyl (6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexyl)carbamate
tert-Butyl N-[6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexyl]carbamate
Carbamic acid, [6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)hexyl]-, 1,1-dimethylethyl ester (9CI)
[Molecular Formula]

C15H24N2O4
[MDL Number]

MFCD22683316
[MOL File]

124529-64-2.mol
[Molecular Weight]

296.36
Chemical PropertiesBack Directory
[Boiling point ]

445.8±28.0 °C(Predicted)
[density ]

1.120±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[pka]

12.92±0.46(Predicted)
Hazard InformationBack Directory
[Uses]

Mal-C4-NH-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

Alkyl/ether
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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