| Identification | Back Directory | [Name]
Carbonic acid 5-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-2,4-bis(1,1-dimethylethyl)phenyl methyl ester | [CAS]
1246213-45-5 | [Synonyms]
Ivacaftor Methylcarbonate
N-[5-(Methoxycarbonyloxy)-2,4-di(tert-butyl)phenyl]-4-oxo-1H-quinoline-3-carboxamide
2,4-di-tert-butyl-5-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl methyl carbonate
Carbonic acid 5-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]amino]-2,4-bis(1,1-dimethylethyl)phenyl methyl ester | [Molecular Formula]
C26H30N2O5 | [MOL File]
1246213-45-5.mol | [Molecular Weight]
450.53 |
| Chemical Properties | Back Directory | [Boiling point ]
583℃ | [density ]
1.198 | [Fp ]
306℃ | [solubility ]
Acetone, Dichloromethane, Methanol | [form ]
Solid | [pka]
11.60±0.70(Predicted) | [color ]
Foamy |
| Hazard Information | Back Directory | [Uses]
N-[5-(Methoxycarbonyloxy)-2,4-di(tert-butyl)phenyl]-4-oxo-1H-quinoline-3-carboxamide is an intermediate in the synthesis of Ivacaftor (4-tertbutyl-d9) (Major) (I940603). Ivacaftor (4-tertbutyl-d9) (Major) is isotopically labelled form of Ivacaftor (I940600), which is used in the treatment of cystic fibrosis. |
|
|