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1246298-65-6

1246298-65-6 Structure

1246298-65-6 Structure
IdentificationBack Directory
[Name]

7Α-HYDROXY-3-OXO-4-CHOLESTENOIC ACID
[CAS]

1246298-65-6
[Synonyms]

Cholesterol Impurity 40
7Α-HYDROXY-3-OXO-4-CHOLESTENOIC ACID
7α-hydroxy -3-oxo-4-cholestenoic acid
Cholest-4-en-26-oic acid, 7-hydroxy-3-oxo-, (7α,25R)-
[Molecular Formula]

C27H42O4
[MDL Number]

MFCD22416721
[MOL File]

1246298-65-6.mol
[Molecular Weight]

430.63
Chemical PropertiesBack Directory
[Boiling point ]

590.5±33.0 °C(Predicted)
[density ]

1.12±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C
[form ]

powder
[pka]

4.81±0.21(Predicted)
Hazard InformationBack Directory
[Uses]

7α-Hydroxy-3-oxo-4-cholestenoic Acid is a bile acid precursor and is found in cerebrospinal fluid of Alzheimer’s patients and may be used in detection.
[Biological Activity]

The levels of 7α-hydroxy-3-oxo-4-cholestenoic acid (7-HOCA) in cerebrospinal fluid are not correlated to neurodegeneration but may serve as a diagnostic marker to trace blood-brain barrier integrity.
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