| Identification | Back Directory | [Name]
cholest-5-ene-3,22(R)-diol-d7 | [CAS]
1246302-93-1 | [Synonyms]
22(R)-hydroxycholesterol-d7
cholest-5-ene-3,22(R)-diol-d7
cholest-5-ene-3β,22(R)-diol-d7
CHOLEST-5-ENE-3,22(R)-DIOL-D7;22(R)-HYDROXYCHOLESTEROL-D7 | [Molecular Formula]
C27H46O2 | [MDL Number]
MFCD22416730 | [MOL File]
1246302-93-1.mol | [Molecular Weight]
402.66 |
| Hazard Information | Back Directory | [Uses]
lipidomics
metabolomics | [Biological Activity]
22(R)-hydroxycholesterol (22(R)-HC) is a liver X receptor (LXR) ligand and is a key for the receptor activation.. 22(R)-HC promotes mesenchymal stem cell osteogenesis along with other oxysterols. It also regulates cholesterol homeostasis and suppresses prostate tumor progression. Low levels of 22(R)-HC is observed in Alzheimerμs disease and may be implicated in neuroinflammation and neurodegenerative diseases. |
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