| Identification | Back Directory | [Name]
Praziquantel-d11 | [CAS]
1246343-36-1 | [Synonyms]
Cesol-d11
Azinox-d11
Droncit-d11
WarMnil-d11
Prazinon-d11
Pyquiton-d11
Cysticide-d11
Distocide-d11
EMbay 8440-d11
Biltricide-d11
Praziquantel-d11
[2H11]-Praziquantel
Praziquantel-(cyclohexyl-d11)
Praziquantel-d11 ((S)-Praziquantel-d11 & (R)-Praziquantel-d11 also available)
2-(Cyclohexyl-d11-carbonyl)-1,2,3,6,7-11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one
2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-(pyrazino-d11)[2,1-a]isoquinolin-4-one
4H-Pyrazino[2,1-a]isoquinolin-4-one, 2-(cyclohexyl-d11-carbonyl)-1,2,3,6,7,11b-hexahydro-
2-(1,2,2,3,3,4,4,5,5,6,6-undecadeuteriocyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one | [Molecular Formula]
C19H24N2O2 | [MDL Number]
MFCD19705058 | [MOL File]
1246343-36-1.mol | [Molecular Weight]
312.406 |
| Chemical Properties | Back Directory | [Melting point ]
133-137°C | [storage temp. ]
2-8°C | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | [form ]
neat | [color ]
White to Pale Beige |
| Hazard Information | Back Directory | [Description]
Praziquantel-d11 is intended for use as an internal standard for the quantification of praziquantel by GC- or LC-MS. Praziquantel is an anthelmintic agent. It is lethal to S. mansoni schistosomula and adults (LC50s = 0.68 and 0.03 mg/ml, respectively). Praziquantel (172 and 592 mg/kg) reduces worm burden in a mouse model of S. mansoni infection. Formulations containing praziquantel have been used in the treatment of schistosomiasis. | [Chemical Properties]
Off-White Solid | [Uses]
As Labelled Praziquantel (P702095), Praziquantel-d11 can beused as Anthelmintic, effective against flatworms.
| [Uses]
Praziquantel-d11 can be intended for use as an internal standard for the quantification of Praziquantel by GC- or LC-mass spectrometry.
| [IC 50]
Schistosome | [References]
[1] COOK G C. Anthelminthic agents: some recent developments and their clinical application.[J]. Postgraduate Medical Journal, 1991, 67 783: 16-22. DOI: 10.1136/pgmj.67.783.16
[2] PIERO OLLIARO J K Petra Delgado Romero. The little we know about the pharmacokinetics and pharmacodynamics of praziquantel (racemate and R-enantiomer).[J]. The Journal of antimicrobial chemotherapy, 2014: 863-870. DOI: 10.1093/jac/dkt491 |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|