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1246461-10-8

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1246461-10-8 Structure

1246461-10-8 Structure
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[Name]

Mtb-cyt-bd oxidase-IN-6
[CAS]

1246461-10-8
[Synonyms]

Mtb-cyt-bd oxidase-IN-6
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[Uses]

Mtb-cyt-bd oxidase-IN-6 is a potent Mycobacterium tuberculosis (Mtb) cytochrome bd (cyt-bd) oxidase (MtbCyt-bd Oxidase) inhibitor with an IC50 value of 0.35 μM. Mtb-cyt-bd oxidase-IN-6 can effectively inhibit the growth of Mtb (MIC= 4 μM). Mtb-cyt-bd oxidase-IN-6 can be used in the study of tuberculosis[1].
[References]

[1] Lawer A, et, al. Synthesis and Biological Evaluation of Aurachin D Analogues as Inhibitors of Mycobacterium tuberculosis Cytochrome bd Oxidase. ACS Med Chem Lett. 2022 Sep 26;13(10):1663-1669. DOI:10.1021/acsmedchemlett.2c00401
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