| Identification | Back Directory | [Name]
Pyrrolidine Ricinoleamide | [CAS]
1246776-23-7 | [Synonyms]
Pyrrolidine Ricinoleamide
(Z,12R)-12-hydroxy-1-pyrrolidin-1-yloctadec-9-en-1-one | [Molecular Formula]
C22H41NO2 | [MOL File]
1246776-23-7.mol | [Molecular Weight]
351.57 |
| Chemical Properties | Back Directory | [Boiling point ]
506.5±33.0 °C(Predicted) | [density ]
0.958±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml | [pka]
15.10±0.20(Predicted) |
| Hazard Information | Back Directory | [Description]
Ricinoleic acid is a naturally occurring 12-hydroxy fatty acid. It constitutes about 90% of the fatty acids in castor oil. Pyrrolidine ricinoleamide is a derivative of the amide of ricinoleic acid that shows potent antiproliferative activity against an array of cancer cell lines, including human glioma U251 cells.1 | [Uses]
Pyrrolidine ricinoleamide ((R)-5d) is a fatty acid amide that exhibits effective antiproliferative activity against a series of cancer cells, including human glioma U251 cells. Pyrrolidine ricinoleamide can be used in cancer research[1]. | [storage]
Store at -20°C | [References]
1. dos Santos, D.S., Piovesan, L.A., D'Oca, C.R.M., et al. Antiproliferative activity of synthetic fatty acid amides from renewable resources Bioorg. Med. Chem. 23(2),340-347(2015). |
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