| Identification | Back Directory | [Name]
hypeptin | [CAS]
124883-38-1 | [Synonyms]
hypeptin
L-Isoleucine, L-alanyl-D-leucyl-D-arginyl-(3R)-3-hydroxy-L-asparaginyl-(3R)-3-hydroxy-D-asparaginyl-(βS)-β-hydroxy-L-tyrosyl-(3R)-3-hydroxy-L-leucyl-, (8→5)-lactone | [Molecular Formula]
C44H71N13O15 | [MDL Number]
MFCD00886574 | [MOL File]
124883-38-1.mol | [Molecular Weight]
1022.11 |
| Hazard Information | Back Directory | [Uses]
Hypeptin is a cyclo-deposited peptide antibiotic produced by Lysobacter sp.K5869. Hypeptin blocks bacterial cell wall biosynthesis by binding to multiple undecaprenyl pyrophosphate-containing biosynthesis intermediates，forming a stoichiometric 2:1 complex. Hypeptin has antibacterial activity[1]. | [References]
[1] Wirtz DA, et al. Biosynthesis and Mechanism of Action of the Cell Wall Targeting Antibiotic Hypeptin. Angew Chem Int Ed Engl. 2021 Jun 7;60(24):13579-13586. DOI:10.1002/anie.202102224 |
|
|