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125-28-0

125-28-0 Structure

125-28-0 Structure
IdentificationBack Directory
[Name]

DIHYDROCODEINE TRIFLUOROACETATE
[CAS]

125-28-0
[Synonyms]

Didrate
Drocode
Nadeine
Parzone
Drocade
Novcodin
Dihydrin
Cohydrin
Dehacodin
Novicodin
Rapacodin
Rapocodin
Paracodin
Paracodine
Novicondin
Hydrocodin
DH-codeine
Codhydrine
Novicodine
NSC 231319
α-Hydrocodol
Hydrocodeine
6α-Hydrocodol
Dihydrokodein
Dihydroneopine
alpha-Hydrocodol
Codeine, dihydro-
6alpha-Hydrocodol
7,8-dihydro-codein
7,8-Dihydrocodeine
6-alpha-hydrocodol
Dihydrocodeine HCl
8,14-Dihydroneopine
Dihydrocodeine (CRM)
RBOXVHNMENFORY-DNJOTXNNSA-N
Codeine, 7,8-dihydro- (6CI)
DIHYDROCODEINE TRIFLUOROACETATE
Dihydrocodeine hydrochloride solution
Dihydrocodeine (base and/or unspecified salts)
6-Hydroxy-3-methoxy-N-methyl-4,5-epoxymorphinan
4,5alpha-Epoxy-3-methoxy-17-methylmorphinan-6alpha-ol
Morphinan-6α-ol, 4,5α-epoxy-3-methoxy-17-methyl- (8CI)
4,5-alpha-epoxy-3-methoxy-17-methyl-morphinan-6-alpha-o
Morphinan-6-ol, 4,5-epoxy-3-methoxy-17-methyl-, (5α,6α)-
Morphinan-6alpha-ol, 4,5alpha-epoxy-3-methoxy-17-methyl-
Morphinan-6-ol, 4,5-epoxy-3-methoxy-17-methyl-, (5alpha,6alpha)-
3-Methoxy-12-methyl-5,6,7,7α,8,9-hexahydro-4aH-8,9c-iminoethanophenanthro[4,5-bcd]furan-5-ol
[EINECS(EC#)]

204-732-3
[Molecular Formula]

C20H24F3NO4
[MDL Number]

MFCD02253008
[MOL File]

125-28-0.mol
[Molecular Weight]

399.4
Chemical PropertiesBack Directory
[Melting point ]

112-113°
[Boiling point ]

bp15 248°
[density ]

1.1412 (rough estimate)
[refractive index ]

1.5740 (estimate)
[Fp ]

9℃
[storage temp. ]

2-8°C
[solubility ]

DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 10 mg/ml
[form ]

A neat solid
[EPA Substance Registry System]

Morphinan-6-ol, 4,5-epoxy-3-methoxy-17-methyl-, (5?,6?)- (125-28-0)
Safety DataBack Directory
[Hazard Codes ]

F,T
[Risk Statements ]

11-23/24/25-39/23/24/25
[Safety Statements ]

7-16-36/37-45
[RIDADR ]

UN1230 - class 3 - PG 2 - Methanol, solution
[REACH Registrations]

Active
[Safety Profile]

Poison by ingestion, intravenous, and subcutaneous routes. Human systemic effects by ingestion and subcutaneous routes: somnolence, miosis (pupillary constriction), and respiratory depression. An analgesic. Can cause drug dependency with repeated doses. When heated to decomposition it emits toxic fumes of NOx. See also CODEINE.
Hazard InformationBack Directory
[Description]

Dihydrocodeine (CRM) (Item No. ISO60142) is a certified reference material categorized as an opioid.1 Dihydrocodeine is an active metabolite of hydrocodone (Item Nos. ISO60144 | 15461 | 22166).2 Formulations containing dihydrocodeine have been used in the treatment of severe pain and have been associated with misuse and polypharmacy-related overdose.3 Dihydrocodeine is regulated as a Schedule II compound in the United States. Dihydrocodeine (CRM) (Item No. ISO60142) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.WARNING This product is not for human or veterinary use.
[Description]

Dihydrocodeine (Item No. 15460) is an analytical reference material categorized as an opioid.1 Dihydrocodeine is an active metabolite of hydrocodone (Item Nos. ISO60144 | 15461 | 22166).2 Formulations containing dihydrocodeine have been used in the treatment of severe pain and have been associated with misuse and polypharmacy-related overdose.3 Dihydrocodeine is regulated as a Schedule II compound in the United States. This product is intended for research and forensic applications.WARNING This product is not for human or veterinary use.
[Description]

Dihydrocodeine (Item No. 37884) is an analytical reference standard categorized as an opioid.1 Dihydrocodeine is an active metabolite of hydrocodone (Item Nos. ISO60144 | 15461 | 22166).2 Formulations containing dihydrocodeine have been used in the treatment of severe pain and have been associated with misuse and polypharmacy-related overdose.3 Dihydrocodeine is regulated as a Schedule II compound in the United States. This product is intended for research and forensic applications.WARNING This product is not for human or veterinary use.
[Originator]

Bicodein,Uquifa
[Definition]

ChEBI: Dihydrocodeine is a morphinane alkaloid.
[Manufacturing Process]

The codein was reduced by hydrogen in the presence catalyst Pt (or Pd, or Ni) and 7,8-dihydrocodein was obtained.
To the 7,8-dihydrocodein tartaric acid was added and mixed, in the result 7,8- dihydrocodein bitartrate was obtained.
[Therapeutic Function]

Antitussive, Narcotic analgesic
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