| Hazard Information | Back Directory | [Description]
JNJ-28610244 is a specific H4 receptor agonist that acts by blocking Mac-1-dependent activation of p38 MAPK. | [Uses]
JNJ 28610244 is a H4R agonist, with a pKi of 7.3 and pEC50 of 7.0, respectively[1]. | [References]
[1] Karim Dib, et al. The histamine H4 receptor is a potent inhibitor of adhesion-dependent degranulation in human neutrophils. J Leukoc Biol. 2014 Sep;96(3):411-8. DOI:10.1189/jlb.2AB0813-432RR |
|
|