| Identification | Back Directory | [Name]
N-(4-Fluorophenyl)-6-morpholino-9H-purin-2-amine | [CAS]
1251578-67-2 | [Synonyms]
Topoisomerase
N-(4-Fluorophenyl)-6-morpholino-9H-purin-2-amine
9H-Purin-2-amine, N-(4-fluorophenyl)-6-(4-morpholinyl)- | [Molecular Formula]
C15H15FN6O | [MDL Number]
MFCD22608428 | [MOL File]
1251578-67-2.mol | [Molecular Weight]
314.32 |
| Chemical Properties | Back Directory | [Boiling point ]
637.4±65.0 °C(Predicted) | [density ]
1.461±0.06 g/cm3(Predicted) | [storage temp. ]
Store at 0-8 °C | [form ]
Powder | [pka]
10.96±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
Topoisomerase IIα-IN-8 (compound 15) is a weak human DNA topoisomerase IIa (htIIa) inhibitor, with an IC50 of 462 ± 38.0 μM[1]. | [IC 50]
topoisomerase II alpha | [References]
[1] Barbara Pogorel?nik, et al. Discovery of Mono- and Disubstituted 1H-Pyrazolo[3,4]pyrimidines and 9H-Purines as Catalytic Inhibitors of Human DNA Topoisomerase?II. ChemMedChem, 2015. |
|
| Company Name: |
Matrix Scientific
|
| Tel: |
803 788-9494 All other calls |
| Website: |
www.matrixscientific.com |
|