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1251957-89-7

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1251957-89-7 Structure

1251957-89-7 Structure
IdentificationBack Directory
[Name]

Benzamide, N-(aminoiminomethyl)-4-[(E)-(3-ethyl-2,4,4-trimethyl-2-cyclohexen-1-ylidene)methyl]-
[CAS]

1251957-89-7
[Synonyms]

Benzamide, N-(aminoiminomethyl)-4-[(E)-(3-ethyl-2,4,4-trimethyl-2-cyclohexen-1-ylidene)methyl]-
[Molecular Formula]

C20H27N3O
[MOL File]

1251957-89-7.mol
[Molecular Weight]

325.45
Chemical PropertiesBack Directory
[Melting point ]

165-167 °C
[density ]

1.10±0.1 g/cm3(Predicted)
[pka]

11.59±0.46(Predicted)
Hazard InformationBack Directory
[Uses]

Magmas-IN-1 (compound 9) is a small molecule Magmas inhibitor (SMMI). Magmas is mitochondria associated，granulocyte-macrophage colony stimulating factor signaling molecule，as well as a GM-CSF inducible gene in myeloid cells. Magmas-IN-1 inhibits Magmas and modulates mitochondrial function. Magmas-IN-1 also inhibits proliferation in yeast at 4 μM[1].
[References]

[1] Jubinsky PT, et al. Design, synthesis, and biological activity of novel Magmas inhibitors. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3479-82. DOI:10.1016/j.bmcl.2011.03.050
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