ChemicalBook--->CAS DataBase List--->1253-43-6

1253-43-6

1253-43-6 Structure

1253-43-6 Structure
IdentificationBack Directory
[Name]

cortisol 21-sulfate
[CAS]

1253-43-6
[Synonyms]

Cortisol sulfate
cortisol 21-sulfate
Cortisol 21-(Hydrogen Sulfate)
11β,17α-Dihydroxypregn-4-ene-3,20
Hydrocortisone 21-sulfate potassium salt
11β,17-Dihydroxy-3,20-diketopregn-4-ene-21-yl Sulfate
11β,17α-Dihydroxy-3,20-diketopregn-4-ene-21-yl Sulfate
(11β)-11,17-Dihydroxy-21-(sulfooxy)pregn-4-ene-3,20-dione
Pregn-4-ene-3,20-dione, 11,17-dihydroxy-21-(sulfooxy)-, (11β)-
[Molecular Formula]

C21H30O8S
[MOL File]

1253-43-6.mol
[Molecular Weight]

442.52
Hazard InformationBack Directory
[Uses]

Cortisol 21-Sulfate is a phase II metabolite of Cortisol (H714615).
[Definition]

ChEBI: A steroid sulfate obtained by the formal condensation of hydroxy group at position 21 of cortisol with sulfuric acid.
[in vivo]

Cortisol sulfate (3 mg; i.m.; every other day; for 2-7 weeks) affects behavior through its direct action on the central nervous system[4].

Animal Model:Male Wistar-King rats[4]
Dosage:3 mg
Administration:Intramuscular injection, every other day, for 2-7 weeks
Result:Had significant stimulatory effects on the animal's exploratory behaviors (ambulation and rearing), when the treatments were started soon after weaning (postnatal day 21-24).
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