| Identification | Back Directory | [Name]
Sitagliptin DeaMino IMpurity 1 | [CAS]
1253056-18-6 | [Synonyms]
Impurity FP-D
Sitagliptin iMpurity S
Sitagliptin Impurity 01
Sitagliptin FP Impurity D
Sitagliptin Impurity FP-D
Sitagliptin EP Impurity 13
Sitagliptin EP Impurity FP-D
Sitagliptin DeaMino IMpurity 1
3-Desamino-2,3-dehydro Sitagliptin
Sitagliptin phenyl crotonyl analog
Sitagliptin USPPhenylcrotonyl Analog
(E)-1-(3-(trifluoromethyl)-5,6-dihydro
(2E)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one
(E)-1-(3-(trifluoroMethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)but-2-en-1-one
2-Buten-1-one, 1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-, (2E)-
(E)-1-(3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)but-2-en-1-one (Sitagliptin Impurity)
Sitagliptin impurity 8/Sitagliptin FP Impurity D/3-Desamino-2,3-Dehydro Sitagliptin/(2E)-1-[3-(Trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)but-2-en-1-one | [EINECS(EC#)]
604-604-1 | [Molecular Formula]
C16H12F6N4O | [MDL Number]
MFCD28972394 | [MOL File]
1253056-18-6.mol | [Molecular Weight]
390.28 |
| Chemical Properties | Back Directory | [Boiling point ]
517.5±60.0 °C(Predicted) | [density ]
1.52±0.1 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol | [form ]
Solid | [pka]
-0.06±0.20(Predicted) | [color ]
Colourless to Pale Yellow Gel to Waxy | [Stability:]
Hygroscopic | [InChI]
InChI=1S/C16H12F6N4O/c17-10-7-12(19)11(18)6-9(10)2-1-3-14(27)25-4-5-26-13(8-25)23-24-15(26)16(20,21)22/h1,3,6-7H,2,4-5,8H2/b3-1+ | [InChIKey]
QSSHJJFVCWMIKH-HNQUOIGGSA-N | [SMILES]
C(N1CCN2C(C(F)(F)F)=NN=C2C1)(=O)/C=C/CC1=CC(F)=C(F)C=C1F |
| Hazard Information | Back Directory | [Uses]
3-Desamino-2,3-dehydro Sitagliptin is an impurity of Sitagliptin (S491000); a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes. |
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| Company Name: |
LANSPHARMA
|
| Tel: |
+91-9000766909 |
| Website: |
www.lanspharma.com |
|