| Identification | Back Directory | [Name]
AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS-OH | [CAS]
125366-42-9 | [Synonyms]
AC-MBP (1-11)
AC-ASQKRPSQRSK
AC-ASQKRPSQRSK-OH
MBP (1-11), MOUSE
ACETYL-MYELIN BASIC PROTEIN (MOUSE, 1-11)
AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS
MYELIN BASIC PROTEIN (2-12) ACETYL [MUS MUSCULUS]
AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-SER-LYS-OH
L-Lysine, N-acetyl-L-alanyl-L-seryl-L-glutaminyl-L-lysyl-L-arginyl-L-prolyl-L-seryl-L-glutaminyl-L-arginyl-L-seryl- (9CI) | [Molecular Formula]
C53 H95 N21 O18 | [MDL Number]
MFCD08274100 | [MOL File]
125366-42-9.mol | [Molecular Weight]
1314.45 |
| Hazard Information | Back Directory | [Uses]
Ac-MBP 1-11, a short peptide sequence, is the major encephalitogenic epitope in myelin basic protein (MBP)[1]. | [References]
[1] Offner H, et al. Estrogen potentiates treatment with T-cell receptor protein of female mice with experimental encephalomyelitis. J Clin Invest. 2000 May;105(10):1465-72. DOI:10.1172/JCI9213
[2] Adlard K, et al. Immunoregulation of encephalitogenic MBP-NAc1-11-reactive T cells by CD4+ TCR-specific Tcells involves IL-4, IL-10 and IFN-gamma. Autoimmunity. 1999;31(4):237-48. DOI:10.3109/08916939908994069 |
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