ChemicalBook--->CAS DataBase List--->1253901-26-6

1253901-26-6

1253901-26-6 Structure

1253901-26-6 Structure
IdentificationBack Directory
[Name]

AC-265347 (AC265347)
[CAS]

1253901-26-6
[Synonyms]

AC-265347 (AC265347)
α-(2,4-Dimethylphenyl)-α-methyl-2-benzothiazolemethanol
[Molecular Formula]

C17H17NOS
[MDL Number]

MFCD20527324
[MOL File]

1253901-26-6.mol
[Molecular Weight]

283.39
Chemical PropertiesBack Directory
[Boiling point ]

448.3±45.0 °C(Predicted)
[density ]

1?+-.0.06 g/cm3(Predicted)
[storage temp. ]

Store at 4°C
[solubility ]

DMSO: 100 mM,Ethanol: 100 mM
[form ]

A solid
[pka]

12.07±0.29(Predicted)
[color ]

Off-white to light yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H319
[Precautionary statements ]

P264-P280-P305+P351+P338-P337+P313P
Hazard InformationBack Directory
[Uses]

AC-265347 is a CaSR (calcium-sensing receptor) activator and allosteric agonist.
[Biological Activity]

AC-265347 is a calcimimetic th at acts as agonist to calcium-sensing receptor. It reduces serum parathyroid hormone and plasma ionizable calcium.''AC-265347 is a human calcium-sensing receptor (CaSR) allosteric agonist. AC-265347 activates CaSR signaling in cellular proliferation and phosphatidyl inositol (PI) hydrolysis assays.
[storage]

Store at +4°C
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