| Identification | Back Directory | [Name]
2H-1-Benzopyran-2-one, 3-[(2E)-3-(2-chlorophenyl)-1-oxo-2-propen-1-yl]- | [CAS]
1253978-24-3 | [Synonyms]
MAO-B-IN-2
2H-1-Benzopyran-2-one, 3-[(2E)-3-(2-chlorophenyl)-1-oxo-2-propen-1-yl]- | [Molecular Formula]
C18H11ClO3 | [MOL File]
1253978-24-3.mol | [Molecular Weight]
310.73 |
| Chemical Properties | Back Directory | [Boiling point ]
524.0±50.0 °C(Predicted) | [density ]
1.367±0.06 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [solubility ]
DMSO : 5 mg/mL (16.09 mM; ultrasonic and warming and heat to 60°C) | [form ]
Solid | [color ]
White to yellow |
| Hazard Information | Back Directory | [Uses]
MAO-B-IN-2 is a selective and competitive inhibitor of MAO-B and BChE with IC50 values of 0.51 and 7.00 μM, respectively. | [Biological Activity]
MAO-B-IN-2 is a selective and competitive inhibitor of MAO-B and BChE with IC50 values of 0.51 and 7.00 μM, respectively. | [References]
[1]. Rehuman NA, et al. Halogenated Coumarin-Chalcones as Multifunctional Monoamine Oxidase-B and Butyrylcholinesterase Inhibitors. ACS Omega. 2021 Oct 12;6(42):28182-28193. |
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