ChemicalBook--->CAS DataBase List--->125399-82-8

125399-82-8

125399-82-8 Structure

125399-82-8 Structure
IdentificationBack Directory
[Name]

altemicidin
[CAS]

125399-82-8
[Synonyms]

altemicidin
1H-Cyclopenta[c]pyridine-7-carboxylic acid, 4-(aminocarbonyl)-7-[[2-(aminosulfonyl)acetyl]amino]-2,4a,5,6,7,7a-hexahydro-6-hydroxy-2-methyl-, (4aR,6S,7R,7aS)-
[Molecular Formula]

C13H20N4O7S
[MDL Number]

MFCD00886596
[MOL File]

125399-82-8.mol
[Molecular Weight]

376.39
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

Ethanol: soluble
[form ]

A powder
Hazard InformationBack Directory
[Uses]

Altemicidin is a monoterpene alkaloid originally isolated from S. sioyaensis with acaricidal and anticancer activities. It is acaricidal to two-spotted spider mites (T. urticae) in a greenhouse pot test at concentrations of 10 and 100 ppm. Altemicidin inhibits the growth of murine L1210 lymphocytic leukemia and IMC carcinoma cells (IC50s=0.84 and 0.82 μg/mL, respectively). It is toxic to mice with an LD50 value of 0.3 mg/kg.
[References]

[1] Takahashi, et al. Altemicidin, a new acaricidal and antitumor substance. I. Taxonomy, fermentation, isolation and physico-chemical and biological properties. J. Antibiot. (Tokyo) 42(11), 1556-1561 (1989).
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