| Identification | Back Directory | [Name]
4-amino-N-[(1S)-1-cyano-2-[4-(4-cyanophenyl)phenyl]ethyl]oxane-4-carboxamide | [CAS]
1254318-44-9 | [Synonyms]
AZD-5248
(AZD5248)
4-amino-N-[(1S)-1-cyano-2-[4-(4-cyanophenyl)phenyl]ethyl]oxane-4-carboxamide | [Molecular Formula]
C22H22N4O2 | [MOL File]
1254318-44-9.mol | [Molecular Weight]
374.436 |
| Hazard Information | Back Directory | [Description]
AZD-5248 is a potent, selective, first generation, oral inhibitor of dipeptidyl peptidase 1 (DPP1). | [Uses]
AZD5248 is a dipeptidyl peptidase 1 (DPP1) inhibitor that can be used for the research of chronic obstructive lung disease[1]. | [storage]
Store at -20°C | [References]
[1] Bragg RA, et al. Aortic Binding of AZD5248: Mechanistic Insight and Reactivity Assays To Support Lead Optimzation. Chem Res Toxicol. 2015 Oct 19;28(10):1991-9. DOI:10.1021/acs.chemrestox.5b00236 |
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