| Identification | Back Directory | [Name]
N4-Benzoyl-7'-OH-N-trityl Morpholino cytosine | [CAS]
125515-31-3 | [Synonyms]
PMO-C Precusor
N4-Benzoyl-7'-OH-N-trityl Morpholino cytosine
N4-Benzoyl-7'-hydroxymorpholino cytidine monomer
N4-Benzoyl-7'-hydroxy-N-trityl-morpholino cytosine monomer
N-(1-(6-(hydroxymethyl)-4-tritylmorpholin-2-yl)-2-oxo-1, 2-dihydropyrimidin-4-yl)benzamide
N-{1-[(2R,6)-6-(hydroxymethyl)-4tritylmorpholin-2-yl]-2-oxo-1,2-dihydropyrimidin-4-yl}benzamide
N-[1-[(2R,6S)-6-(Hydroxymethyl)-4-tritylmorpholin-2-yl]-2-oxo-1,2-dihydropyrimidine-4-yl]benzamide
Benzamide, N-[1,2-dihydro-1-[(2R,6S)-6-(hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl]-2-oxo-4-pyrimidinyl]- | [Molecular Formula]
C35H32N4O4 | [MDL Number]
MFCD22666302 | [MOL File]
125515-31-3.mol | [Molecular Weight]
572.65 |
| Chemical Properties | Back Directory | [density ]
1.24±0.1 g/cm3(Predicted) | [pka]
8.65±0.20(Predicted) | [InChIKey]
DMFVVKPXZHMPKX-XDFJSJKPSA-N | [SMILES]
C(NC1C=CN([C@@H]2O[C@H](CO)CN(C(C3=CC=CC=C3)(C3=CC=CC=C3)C3=CC=CC=C3)C2)C(=O)N=1)(=O)C1=CC=CC=C1 |
| Hazard Information | Back Directory | [Uses]
N4-Benzoyl-7’-OH-N-trityl morpholino cytosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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