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1255303-58-2

1255303-58-2 Structure

1255303-58-2 Structure
IdentificationBack Directory
[Name]

c-Fms-IN-8
[CAS]

1255303-58-2
[Synonyms]

cFmsIN8,c Fms IN 8
[Molecular Formula]

C27H30N2O5
[MDL Number]

MFCD32067931
[MOL File]

1255303-58-2.mol
[Molecular Weight]

462.54
Chemical PropertiesBack Directory
[Boiling point ]

671.2±55.0 °C(Predicted)
[density ]

1.230±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

13.89±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

c-Fms-IN-8 (compound 4a) is a colony stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor, with an IC50 of 9.1 nM[1]. IC50: 9.1 nM (CSF-1R)[1].

[Uses]

c-Fms-IN-8 (compound 4a) is a colony stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor, with an IC50 of 9.1 nM[1].
[References]

[1]. Ikegashira K, et al. Discovery of a novel azetidine scaffold for colony stimulating factor-1 receptor (CSF-1R) Type II inhibitors by the use of docking models. Bioorg Med Chem Lett. 2019 Jan 1;29(1):115-118.

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