| Identification | Back Directory | [Name]
MVT 101 | [CAS]
125552-93-4 | [Synonyms]
N-1465
MVT 101
Ac-L-Thr-L-Ile-L-Nleψ(CH2NH)-L-Nle-L-Gln-L-Arg-NH2
N-Ac-L-Thr-L-Ile-[(2S)-2-Amino*hexyl]-L-Nle-L-Gln-L-Arg-NH2
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S,3R)-2-acetamido-3-hydroxybutanoyl]amino]-3-methylpentanoyl]amino]hexyl]amino]hexanoyl]amino]-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamide | [Molecular Formula]
C35H67N11O8 | [MOL File]
125552-93-4.mol | [Molecular Weight]
769.99 |
| Hazard Information | Back Directory | [Description]
Mvt 101 is a peptide inhibitor. | [Uses]
Mvt-101 is a hexapeptide-based inhibitor of HIV-1 protease. Mvt-101 is also reduced-peptide-bond inhibitor. Mvt-101 inhibits reproduction of the HIV virus by blocking protease action[1]. | [References]
[1] Torbeev VY, et al. Protein conformational dynamics in the mechanism of HIV-1 protease catalysis. Proc Natl Acad Sci USA. 2011 Dec 27;108(52):20982-7. DOI:10.1073/pnas.1111202108 |
|
|