| Identification | Back Directory | [Name]
1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)- | [CAS]
1256094-31-1 | [Synonyms]
AI-10-47
1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-
2-(Pyridin-2-yl)-6-(trifluoromethoxy)-1H-benzo[d]imidazole
1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-AI-10-47 | [Molecular Formula]
C13H8F3N3O | [MDL Number]
MFCD34167535 | [MOL File]
1256094-31-1.mol | [Molecular Weight]
279.22 |
| Chemical Properties | Back Directory | [Boiling point ]
411.7±55.0 °C(Predicted) | [density ]
1.439±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
8.87±0.10(Predicted) | [color ]
Off-white to gray |
| Hazard Information | Back Directory | [Description]
AI-10-47 is a novel inhibitor of CBFβ-RUNX binding (IC50 of 3.2 μM). | [Uses]
AI-10-47 is a small molecule inhibitor of CBFβ-RUNX binding, with an IC50 of 3.2 μM[1]. | [References]
[1] Anuradha Illendula, et al. Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers. EBioMedicine. 2016 Jun;8:117-131. DOI:10.1016/j.ebiom.2016.04.032 |
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| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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