| Identification | Back Directory | [Name]
9-ethyl-8-iodo-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile | [CAS]
1256584-80-1 | [Synonyms]
181484
Alectinib Impurity 12
9-ethyl-8-iodo-6,6-dimethyl-11-oxo-5H-benzo[b]carbazole-3-carbonitrile
9-ethyl-8-iodo-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
9-Ethyl-6,6-dimethyl-8-iodo-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
5H-Benzo[b]carbazole-3-carbonitrile, 9-ethyl-6,11-dihydro-8-iodo-6,6-dimethyl-11-oxo-
9-ethyl-8-iodo-6,6-diMethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile-11 | [Molecular Formula]
C21H17IN2O | [MDL Number]
MFCD22124656 | [MOL File]
1256584-80-1.mol | [Molecular Weight]
440.28 |
| Chemical Properties | Back Directory | [Melting point ]
>300°C | [Boiling point ]
612.0±55.0 °C(Predicted) | [density ]
1?+-.0.1 g/cm3(Predicted) | [storage temp. ]
Amber Vial, -20°C Freezer | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
13.47±0.40(Predicted) | [color ]
White to Off-White | [Stability:]
Light Sensitive |
| Hazard Information | Back Directory | [Uses]
9-?Ethyl-?8-?iodo-?6,?6-?dimethyl-?11-?oxo-?6,?11-?dihydro-?5H-?benzo[b]?carbazole-?3-?carbonitrile is an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth. Process impurity. |
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| Company Name: |
SPIRO PHARMA
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| Telephone: |
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| Website: |
www.spiropharma.com.cn |
| Company Name: |
SPIRO PHARMA
|
| Telephone: |
|
| Website: |
www.spiropharma.com.cn |
| Company Name: |
Henan Alfachem Co.,Ltd.
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| Telephone: |
0371-55051623 18137891487 |
| Website: |
www.chemicalbook.com/supplier/14555231/ |
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