1258457-58-7

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1258457-58-7 Structure

Identification	Back Directory
[Name] 1H-Imidazo[4,5-c]quinolin-4-amine, 1-[[3-(aminomethyl)phenyl]methyl]-2-butyl-
[CAS] 1258457-58-7
[Synonyms] 1-(3-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine 1H-Imidazo[4,5-c]quinolin-4-amine, 1-[[3-(aminomethyl)phenyl]methyl]-2-butyl-
[Molecular Formula] C22H25N5
[MOL File] 1258457-58-7.mol
[Molecular Weight] 359.47

Hazard Information	Back Directory
[Uses] m-AM-BBIQ (compound 10) is a dual TLR7 and TLR8 agonist, with EC50 values of 0.12 μM and 1.7 μM for hTLR7 and hTLR8, respectively[1].
[References] [1] Kushvinder Kumar, et al. Modulation of the Adjuvant Potential of Imidazoquinoline-Based TLR7/8 Agonists via Alum Adsorption. ACS Med. Chem. Lett. 2024, July. 22.

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