| Chemical Properties | Back Directory | [Melting point ]
135-137 °C | [Boiling point ]
509.4±50.0 °C(Predicted) | [density ]
1.234±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
4.61±0.20(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
UBS109, as a curcumin analogue, can promote the differentiation and mineralization of osteoblasts. UBS109 shows to regulate bone cell function by activating Smad and inhibiting NF-kB. UBS109 can be used in bone tissue engineering and osteoporosis research[1]. | [References]
[1] Yamaguchi M, et al. Novel curcumin analogue UBS109 potently stimulates osteoblastogenesis and suppresses osteoclastogenesis: involvement in Smad activation and NF-κB inhibition[J]. Integrative biology, 2012, 4(8): 905-913. DOI:10.1039/c2ib20045g |
|
|