| Identification | Back Directory | [Name]
ETHINAMATE | [CAS]
126-52-3 | [Synonyms]
Valmid Valamin Volamin Valamina Valmidate Etinamate usafel-42 Ethinamat Ethinimate ETHINAMATE USAF el-42 valaminetta Valaminettae Valaminetten ETHINAMATE USP/EP/BP ethynylcyclohexylcarbamate GXRZIMHKGDIBEW-UHFFFAOYSA-N 1-ethinylcyclohexylcarbamate 1-ethinylcyclohexylcarbonate 1-ethynylcyclohexylcarbamate Aethinyl-cyclohexyl-carbamat 1-Ethynylcyclohexyl carbamate 1-Ethinylcyclohexyl carbamate 1-ethynyl-cyclohexanocarbamate 1-ETHYNYLCYCLOHEXANOL CARBAMATE carbamatedel’ethinylcyclohexanol ethinamate--dea schedule iv item Carbamate de L'ethinylcyclohexanol Cyclohexanol, 1-ethynyl-, carbamate carbamicacid1-ethynylcyclohexylester carbamicacid,1-ethynylcyclohexylester Cyclohexanol, 1-ethynyl-, 1-carbamate Carbamic acid, 1-ethynylcyclohexyl ester | [EINECS(EC#)]
204-789-4 | [Molecular Formula]
C9H13NO2 | [MDL Number]
MFCD00063343 | [MOL File]
126-52-3.mol | [Molecular Weight]
167.21 |
| Hazard Information | Back Directory | [Definition]
ChEBI: A carbamate ester that is the 1-vinylcyclohexyl ester of carbamic acid. A short-acting sedative-hypnotic, it was formerly used to treat insomnia. | [Originator]
Valmid,Dista,US,1955 | [Uses]
Ethinamate (E890730) is a an active central nervous system depressant used in the treatment of insomnia. | [Manufacturing Process]
A solution of 34 cc (0.5 mol) of liquid phosgene in 150 cc of absolute ether is
reacted while cooling with a mixture of sodium chloride and ice, first with 62
grams (0.5 mol) of 1-ethinyl cyclohexanol-1 and then with 64 cc (0.5 mol) of
quinoline. The precipitated quinoline chlorohydrate is filtered off and the
filtrate is reacted with ammonia in ether. In this manner 45 grams of the
carbamic acid ester of 1-ethinyl cyclohexanol are obtained. Yield: 53% of the
theoretical yield. The ester boils at 108° to 110°C/3 mm and on
recrystallization from cyclohexane, yields colorless needles melting at 94° to
96°C. | [Therapeutic Function]
Sedative |
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