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1260177-41-0

1260177-41-0 Structure

1260177-41-0 Structure
IdentificationBack Directory
[Name]

2-Amino-9-[(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)]-9H-purine
[CAS]

1260177-41-0
[Synonyms]

9-(2',3',5'-Tri-O-benzoyl-b-D-ribofuranosyl)-2-chloropurine
2-Chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-purine
9H-Purine, 2-chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-
2-Amino-9-[(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)]-9H-purine
2-chloro-9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-9H-purine
(2R,3R,4R,5R)-2-(acetoxymethyl)-5-(2-chloro-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate
[Molecular Formula]

C16H17ClN4O7
[MDL Number]

MFCD31707471
[MOL File]

1260177-41-0.mol
[Molecular Weight]

412.78
Chemical PropertiesBack Directory
[Boiling point ]

517.8±60.0 °C(Predicted)
[density ]

1.62±0.1 g/cm3(Predicted)
[pka]

0.16±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

2-Chloro-9-[(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)]-9H-purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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