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1260612-13-2

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1260612-13-2 Structure

1260612-13-2 Structure
IdentificationBack Directory
[Name]

SAR-260301
[CAS]

1260612-13-2
[Synonyms]

SAR-260301
SAR260301,SAR 260301
(S)-2-(2-(2-Methylindolin-1-yl)-2-oxoethyl)-6-MorpholinopyriMidin-4(3H)-one
4(3H)-Pyrimidinone, 2-[2-[(2S)-2,3-dihydro-2-methyl-1H-indol-1-yl]-2-oxoethyl]-6-(4-morpholinyl)-
[Molecular Formula]

C19H22N4O3
[MDL Number]

MFCD27987912
[MOL File]

1260612-13-2.mol
[Molecular Weight]

354.4
Chemical PropertiesBack Directory
[Boiling point ]

595.7±60.0 °C(Predicted)
[density ]

1.38±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:7): 0.12 mg/ml; Ethanol: 15 mg/ml
[form ]

A crystalline solid
[pka]

10.39±0.50(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H317-H335
[Precautionary statements ]

P261-P264-P271-P272-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P333+P313-P337+P313-P363-P403+P233-P405-P501
Hazard InformationBack Directory
[Uses]

SAR 260301 is a phosphatidylinositol 3-kinase (PI3K) isoform β inhibitor. PI3Kβ-specific inhibitors have therapeutic potential for developing treatments against PTEN-deficient cancers.
Spectrum DetailBack Directory
[Spectrum Detail]

SAR-260301(1260612-13-2)1HNMR
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