| Identification | Back Directory | [Name]
N(alpha)-(N(alpha)-(N(alpha)-(tert-butyloxycarbonyl)glutaminyl)-N(1)-formyl-tryptophyl)phenylalanine benzyl ester | [CAS]
126088-82-2 | [Synonyms]
QWF
L-Phenylalanine, N2-[(1,1-dimethylethoxy)carbonyl]-L-glutaminyl-1-formyl-D-tryptophyl-, phenylmethyl ester
N(alpha)-(N(alpha)-(N(alpha)-(tert-butyloxycarbonyl)glutaminyl)-N(1)-formyl-tryptophyl)phenylalanine benzyl ester | [Molecular Formula]
C38H43N5O8 | [MOL File]
126088-82-2.mol | [Molecular Weight]
697.78 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [color ]
White to off-white | [Sequence]
{Boc}-Gln-{d-Trp(Formyl)}-Phe-{OBzl} |
| Hazard Information | Back Directory | [Uses]
QWF Peptide (Compound 4a) is a substance P antagonist with an IC50 of 0.09 μM. QWF Peptide antagonizes the SP-induced contraction of isolated guinea pig trachea strips with an IC50 of 4.7 μM[1]. | [storage]
Store at -20°C | [References]
[1] Hagiwara D, et al. Studies on neurokinin antagonists. 1. The design of novel tripeptides possessing the glutaminyl-D-tryptophylphenylalanine sequence as substance P antagonists. J Med Chem. 1992 May 29;35(11):2015-25. DOI:10.1021/jm00089a011 |
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Fuan Bio
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15002819872 |
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