| Identification | Back Directory | [Name]
Dimiracetam | [CAS]
126100-97-8 | [Synonyms]
ISF4185
NT11624
NT-11624
ISF-4185
BND11624
BND-11624
Espindolol
Dimiracetam
dihydro-1H-Pyrrolo[1,2-a]iMidazole-2,5(3H,6H)-dione
1H-Pyrrolo[1,2-a]imidazole-2,5(3H,6H)-dione, dihydro-
1H-Pyrrolo[1,2-a]imidazole-2,5(3H,6H)-dione, dihydro-（WS201690） | [Molecular Formula]
C6H8N2O2 | [MDL Number]
MFCD00867777 | [MOL File]
126100-97-8.mol | [Molecular Weight]
140.141 |
| Hazard Information | Back Directory | [Uses]
Dimiracetam is an orally active compound, with anti-neuropathic activity. Dimiracetam inhibits hypersensitivity and neurological alterations, and inhibits Sorafenib (HY-10201)-induced neuropathy in cold stimulation rat models[1]. | [References]
[1] Di Cesare Mannelli L, et al. A model of neuropathic pain induced by sorafenib in the rat: Effect of dimiracetam. Neurotoxicology. 2015 Sep;50:101-7. DOI:10.1016/j.neuro.2015.08.002
[2] Di Cesare Mannelli L, et al. A rat model of FOLFOX-induced neuropathy: effects of oral dimiracetam in comparison with duloxetine and pregabalin. Cancer Chemother Pharmacol. 2017 Dec;80(6):1091-1103. DOI:10.1007/s00280-017-3449-8 |
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