| Identification | Back Directory | [Name]
BACE-1 inhibitor 1 | [CAS]
1262858-14-9 | [Synonyms]
BACE-1 inhibitor 1
BACE1 inhibitor 1,BACE 1 inhibitor 1
2-Pyridinecarboxamide, N-[3-[(3R)-5-amino-3-(difluoromethyl)-3,6-dihydro-2H-1,4-oxazin-3-yl]-4-fluorophenyl]-5-bromo- | [Molecular Formula]
C17H14BrF3N4O2 | [MDL Number]
MFCD31813667 | [MOL File]
1262858-14-9.mol | [Molecular Weight]
443.22 |
| Hazard Information | Back Directory | [Uses]
BACE-1 inhibitor 1 (Compound 8a) is a potent BACE-1 inhibitor with an IC50 of 56 nM[1]. | [References]
[1] Veenstra SJ, et al. Discovery of amino-1,4-oxazines as potent BACE-1 inhibitors. Bioorg Med Chem Lett. 2018 Jul 1;28(12):2195-2200. DOI:10.1016/j.bmcl.2018.05.003 |
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