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1262858-14-9

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1262858-14-9 Structure

1262858-14-9 Structure
IdentificationBack Directory
[Name]

BACE-1 inhibitor 1
[CAS]

1262858-14-9
[Synonyms]

BACE-1 inhibitor 1
BACE1 inhibitor 1,BACE 1 inhibitor 1
2-Pyridinecarboxamide, N-[3-[(3R)-5-amino-3-(difluoromethyl)-3,6-dihydro-2H-1,4-oxazin-3-yl]-4-fluorophenyl]-5-bromo-
[Molecular Formula]

C17H14BrF3N4O2
[MDL Number]

MFCD31813667
[MOL File]

1262858-14-9.mol
[Molecular Weight]

443.22
Chemical PropertiesBack Directory
[density ]

1.69±0.1 g/cm3(Predicted)
[pka]

10.04±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

BACE-1 inhibitor 1 (Compound 8a) is a potent BACE-1 inhibitor with an IC50 of 56 nM[1].
[References]

[1] Veenstra SJ, et al. Discovery of amino-1,4-oxazines as potent BACE-1 inhibitors. Bioorg Med Chem Lett. 2018 Jul 1;28(12):2195-2200. DOI:10.1016/j.bmcl.2018.05.003
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Company Name: TargetMol Chemicals Inc.
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Website: https://www.targetmol.com/
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Tel: +17819995354 , +17819995354
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