| Identification | Back Directory | [Name]
DHODH-IN-12 | [CAS]
1263303-93-0 | [Synonyms]
DHODH-IN-12
DHODHIN12,DHODH IN 12
Acetamide, 2-cyano-2-(hydroxyimino)-N-(4-methylphenyl)-, (2E)- | [Molecular Formula]
C10H9N3O2 | [MDL Number]
MFCD06244921 | [MOL File]
1263303-93-0.mol | [Molecular Weight]
203.2 |
| Hazard Information | Back Directory | [Uses]
DHODH-IN-12 (Compound 12b) is a Leflunomide derivative and a weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07[1]. | [References]
[1] Giorgis M, et al. 1,2,5-Oxadiazole analogues of leflunomide and related compounds. Eur J Med Chem. 2011 Jan;46(1):383-92. DOI:10.1016/j.ejmech.2010.10.029 |
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