| Identification | Back Directory | [Name]
Lisavanbulin | [CAS]
1263384-43-5 | [Synonyms]
BAL101553
Lisavanbulin
(S)-2,6-diaminohexanoic acid [4-(2-{2-[4-(2-cyanoethylamino)furazan-3-yl]-benzoimidazol-1-yl}acetyl)phenyl]amide
Hexanamide, 2,6-diamino-N-[4-[2-[2-[4-[(2-cyanoethyl)amino]-1,2,5-oxadiazol-3-yl]-1H-benzimidazol-1-yl]acetyl]phenyl]-, (2S)- | [Molecular Formula]
C26H29N9O3 | [MOL File]
1263384-43-5.mol | [Molecular Weight]
515.57 |
| Hazard Information | Back Directory | [Uses]
Lisavanbulin (BAL-101553) is the prodrug of the microtubule targeting agent Avanbulin (BAL 27862) (HY-106008). Lisavanbulin exhibits antitumor activity, especially in tumors that express high levels of end-binding protein 1[1]. | [References]
[1] Spriano F, et al. Assessment of lisavanbulin (BAL101553) as an anti-lymphoma agent[J]. bioRxiv, 2023: 2022.12. 31.521730. |
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