| Identification | Back Directory | [Name]
methylmalonyl-coenzyme A | [CAS]
1264-45-5 | [Synonyms]
methylmalonyl-coenzyme A
Methylmalonyl-CoA-sodium-salt
Coenzyme A, S-(hydrogen 2-methylpropanedioate) | [Molecular Formula]
C25H40N7O19P3S | [MOL File]
1264-45-5.mol | [Molecular Weight]
867.61 |
| Hazard Information | Back Directory | [Uses]
Methylmalonyl coenzyme A (Methylmalonyl-CoA) is a catabolite of valine, isoleucine, methionine, threonine, odd-chain fatty acids, and cholesterol. Methylmalonyl coenzyme A tetralithium is converted to succinyl-CoA by enzymatic reaction of methylmalonyl-CoA mutase (MCM) with coenzyme vitamin B12[1]. | [Definition]
ChEBI: A member of the class of malonyl-CoAs that is malonyl-CoA carrying a methyl group on the malony side chain. | [References]
[1] Gotoh K, et al. Assay for methylmalonyl coenzyme A mutase activity based on determination of succinyl coenzyme A by ultrahigh-performance liquid chromatography tandem mass spectrometry. Anal Bioanal Chem. 2015 Jul;407(18):5281-6. DOI:10.1007/s00216-015-8753-8 |
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