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1265966-31-1

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1265966-31-1 Structure

1265966-31-1 Structure
IdentificationBack Directory
[Name]

S49076 HCl
[CAS]

1265966-31-1
[Synonyms]

S49076 HCl
S49076 (hydrochloride)
S49076;S-49076;;S 49076
[Molecular Formula]

C22H23ClN4O4S
[MOL File]

1265966-31-1.mol
[Molecular Weight]

474.96
Hazard InformationBack Directory
[Uses]

S49076 hydrochloride is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3 with IC50 values below 20 nM.
[References]

[1] Burbridge MF, et al. S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab. Mol Cancer Ther. 2013 Sep;12(9):1749-62. DOI:10.1158/1535-7163.MCT-13-0075
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