| Identification | Back Directory | [Name]
Quinoxaline, 6,7-difluoro-1,2,3,4-tetrahydro-2-phenyl- | [CAS]
1266755-01-4 | [Synonyms]
Quinoxaline, 6,7-difluoro-1,2,3,4-tetrahydro-2-phenyl- | [Molecular Formula]
C14H12F2N2 | [MOL File]
1266755-01-4.mol | [Molecular Weight]
246.26 |
| Chemical Properties | Back Directory | [Boiling point ]
370.4±42.0 °C(predicted) | [density ]
1.225±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
3.10±0.70(predicted) |
| Hazard Information | Back Directory | [Uses]
Ferroptosis-IN-11 (compound 43) is a ferroptosis inhibitor. Ferroptosis-IN-11 can inhibit Erastin (HY-15763) induced ferroptosis in HT-1080 human fibroblasts (EC50=36 nM). Ferroptosis-IN-11 can be used in the study of cardiovascular disease and neurodegeneration[1]. | [References]
[1] HongXu Lei, et al. "A quantum-chemical approach to develop tetrahydroquinoxaline as potent ferroptosis inhibitors." Journal of Molecular Structure 1228 (2021): 129485. |
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