| Identification | Back Directory | [Name]
fasciculic acid B | [CAS]
126882-55-1 | [Synonyms]
fasciculic acid B
Lanost-8-ene-2,3,12,24,25-pentol, 2-(hydrogen 3-hydroxy-3-methylpentanedioate), (2α,3β,12α,24R)-
4-Carboxylato-3-hydroxy-3-methylbutanoic acid (24R)-3β,12α,24,25-tetrahydroxy-5α-lanost-8-en-2α-yl ester | [Molecular Formula]
C36H60O9 | [MOL File]
126882-55-1.mol | [Molecular Weight]
636.87 |
| Hazard Information | Back Directory | [Description]
Fasciculic acid B is the ester of fasciculol B & 3-hydroxy-3-methylglutaric acid; calmodulin antagonist from mushroom Naematoloma fasciculare. | [Uses]
Fasciculic acid B is a steroid that can be isolated from Hypholoma lateritium. Fasciculic acid B has antiinflammatory and calmodulin antagonistic activity[1][2]. | [Definition]
ChEBI: Fasciculic acid B is a triterpenoid. | [References]
[1] Ványolós A, et al. Extracts and Steroids from the Edible Mushroom Hypholoma lateritium Exhibit Anti-Inflammatory Properties by Inhibition of COX-2 and Activation of Nrf2. Chem Biodivers. 2020 Sep;17(9):e2000391. DOI:10.1002/cbdv.202000391
[2] Takahashi A, et al. Fasciculic acids A, B and C as calmodulin antagonists from the mushroom Naematoloma fasciculare. Chem Pharm Bull (Tokyo). 1989 Dec;37(12):3247-50. DOI:10.1248/cpb.37.3247 |
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