| Identification | Back Directory | [Name]
hikizimycin | [CAS]
12706-94-4 | [Synonyms]
Nsc337588 Aids029905 Aids-029905 hikizimycin 1402-84-2 (Deleted) 1-N-(2-o-(3-Amino-3-deoxy-.beta.-D-glucopyranosyl)-4-amino-4-deoxy-D-glycero-D-gal acto-D-gluco-.beta.-D-undecapyranosyl)cytosine 4-Amino-1-[4-amino-6-O-(3-amino-3-deoxy-β-D-glucopyranosyl)-4-deoxy-D-glycero-D-galacto-β-D-gluco-undecopyranosyl]-2(1H)-pyrimidinone 2(1H)-Pyrimidinone, 4-amino-1-[4-amino-6-O-(3-amino-3-deoxy-β-D-glucopyranosyl)-4-deoxy-D-glycero-D-galacto-β-D-gluco-undecopyranosyl]- 2(1H)-Pyrimidinone, 4-amino-1-[4-amino-6-o-(3-amino-3-deoxy-.beta.-D-glucopyranosyl)-4-deoxy-D-glycero-D-galacto-.beta.-D-gluco-undecopyranosyl]- | [Molecular Formula]
C21H37N5O14 | [MOL File]
12706-94-4.mol | [Molecular Weight]
583.55 |
| Chemical Properties | Back Directory | [Boiling point ]
641.06°C (rough estimate) | [density ]
1.4619 (rough estimate) | [refractive index ]
1.7850 (estimate) | [pka]
12.99±0.70(Predicted) | [color ]
Crystals |
| Hazard Information | Back Directory | [Uses]
Hikizimycin is a potent anthelmintic and antibacterial natural product. | [Definition]
ChEBI: A nucleoside antibiotic with anthelminthic properties that is isolated from Streptomyces longissimus. | [Safety Profile]
Poison by ingestion andintravenous routes. When heated to decomposition itemits toxic fumes of NOx. | [References]
[1] Fujino H, et al. Total Syntheses of Hikosamine and Hikizimycin. J Org Chem. 2021 Dec 3;86(23):16220-16230. DOI:10.1021/acs.joc.1c01773 |
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