| Identification | Back Directory | [Name]
1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDODICARBOCYANINE PERCHLORATE | [CAS]
127274-91-3 | [Synonyms]
DID
'DID'
D 307
DILC18(5)
DIIC18(5)
'DID' OIL
dilC18(5) dye
DIIC18(5) OIL
DiD perchlorate
Lipophilic Dye Did
DiD oil
DiIC18(5) oil
1,1-Dioctadecyl-3,3,3,3-tetramethylindodicarbocyanine
1,1'-dioctadecyl-3,3,3',3'-tetrame.indo-dicarbocyanine clo4
1,1'-Dioctadecyl-3,3,3',3'-tetramethylindodicarbovyanineperchlorate
1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDODICARBOCYANINE PERCHLORATE
1,10-dioctadecyl-
3,3,30,30-tetramethylindodicarbocyanine Perchlorate
1,1''-Dioctadecyl-3,3,3'',3''-tetramethylindodicarbocyanine
perchlorate
1,1-Dioctadecyl-3,3,3,3-tetramethylindodicarbocyanine perchlorate (DiD oil
DiIC18(5) [DiD] [1,1'-Dioctadecyl-3,3,3',3'-tetraMethylindodicarbocyanine perchlorate]
3H-INDOLIUM, 2-[5-(1,3-DIHYDRO-3,3-DIMETHYL-1-OCTADECYL-2H-INDOL-2-YLIDENE)-1,3-PENTADIENYL]-3,3-DIMETHYL-1-OCTADECYL-, PERCHLORATE
2-[5-(1,3-Dihydro-3,3-dimethyl-1-octadecyl-2H-indol-2-ylidene)-1,3-pentadien-1-yl]-3,3-dimethyl-1-octadecyl-3H-indolium perchlorate
3h-indolium, 2-[5-(1,3-dihydro-3,3-dimethyl-
1-octadecyl-2h-indol-2-ylidene)-1,3-pentadienyl]-
3,3-dimethyl-1-octadecyl-, Perchlorate
2-[(1E,3E)-5-(3,3-DIMETHYL-1-OCTADECYL-1,3-DIHYDRO-2H-INDOL-2-YLIDENE)-1,3-PENTADIENYL]-3,3-DIMETHYL-1-OCTADECYL-3H-INDOLIUM PERCHLORATE
3H-Indolium, 2-[5-(1,3-dihydro-3,3-dimethyl-1-octadecyl-2H-indol-2-ylidene)-1,3-pentadien-1-yl]-3,3-dimethyl-1-octadecyl-, perchlorate (1:1) | [Molecular Formula]
C61H99ClN2O4 | [MDL Number]
MFCD00216701 | [MOL File]
127274-91-3.mol | [Molecular Weight]
959.9 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C
| [solubility ]
Soluble in ethanol, methanol, dimethyl
sulfoxide | [form ]
crystals | [color ]
Dark brown | [Appearance]
Blue paint solid | [ex/em]
648/670nm | [ε(extinction coefficient)]
247000 L⋅mol−1⋅cm−1 | [λmax]
644 nm | [Biological Applications]
Detecting cell lysis,microorganisms,nucleic acids,lipid diffusion in giant unilamellar vesicles,lipid diffusion in phospholipid bilayers,lipids and proteins diffusion in membranes; monitoring cell migration | [InChIKey]
ZQSBJPAQPRVNHU-UHFFFAOYSA-M | [SMILES]
C12C=CC=CC=1C(C)(C)/C(=C\C=C\C=C\C1C(C)(C)C3C=CC=CC=3[N+]=1CCCCCCCCCCCCCCCCCC)/N2CCCCCCCCCCCCCCCCCC.Cl([O-])(=O)(=O)=O |
| Hazard Information | Back Directory | [Description]
DiD is a lipophilic fluorescent probe. It is rapidly incorporated into phospholipid cell membranes and has been used to label the plasma membrane and endocytic organelles in bovine aorta endothelial cells and rat hippocampal slices. DiD has also been used to assess proliferation in prostate cancer cell lines by flow cytometry, where high DiD-expressing cell populations are associated with lower proliferation. DiD is not cytotoxic and can be detected in subcutaneously implanted PC3 cells in vivo after three weeks. It displays absorption/emission maxima of 650/670 nm, respectively. | [Chemical Properties]
Appearance: Blue lacquer-like solid
ex/em: 648/670nm
Intracellular distribution: Membrane & lipid
Extinction coefficient (ε): 247000 L??mol??1??cm??1 | [Uses]
Fluorescent lipophilic tracer | [in vivo]
Two weeks after injection of stained cells, a single, bright, DiD perchlorate (DiD)-positive cells located between 15 to 40 μm from the endosteum is found. Results reveal a progressive appearance of cell clusters of decreased dye intensity, consistent with the partitioning of DiD perchlorate label on cell division[3]. | [storage]
Store at -20°C | [Excitation / Emission Maximum]
549 nm/565 nm |
|
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Rhawn Reagent
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Henan Alfachem Co.,Ltd.
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