ChemicalBook--->CAS DataBase List--->127367-76-4

127367-76-4

127367-76-4 Structure

127367-76-4 Structure
IdentificationBack Directory
[Name]

Frondoside A hydrate
[CAS]

127367-76-4
[Synonyms]

Frondoside A hydrate
[Molecular Formula]

C60H95NaO29S
[MDL Number]

MFCD32669862
[MOL File]

127367-76-4.mol
[Molecular Weight]

1335.43
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

H2O: ≥10mg/mL
[form ]

powder
[color ]

white to off-white
[Water Solubility ]

H2O: ≥10mg/mL
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Biochem/physiol Actions]

Frondoside A is a bioactive triterpenoid saponin from sea cucumber; and an immunostimulant. Frondoside A is an extremely potent inducer of apoptosis, and although it does activate caspaces, it can induce apoptosis in HL-60 cells through a mechanism distinct from extrinsic and intrinsic apoptosis pathways. It potentially valuable for cancers that are resistent to other apoptosis inducers, such as pancreatic cancer.
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