| Identification | Back Directory | [Name]
ASP-ALA-PHE-VAL-BETA-ALA-LEU-MET-NH2 | [CAS]
127633-71-0 | [Synonyms]
(ala5
DAFV-(-A)-LM-NH2
DAFV-(BETA-A)-LM-NH2
(β-Ala?)-Neurokinin A (4-10)
Ala5,b-Ala8] Neurokinin A (4-10)
asp-ala-phe-val-β-ala-leu-met-nh2
Ala5, β-Ala8]-Neurokinin A (4-10)
[Ala5, β-Ala8]-Neurokinin A (4-10)
H-Asp-Ser-Phe-Val-b-Ala-Leu-Met-NH2
ASP-ALA-PHE-VAL-BETA-ALA-LEU-MET-NH2
[ALA5, BETA-ALA8]-NEUROKININ A (4-10)
H-ASP-ALA-PHE-VAL-BETA-ALA-LEU-MET-NH2
[ala5, β-ala8]-α-neurokinin fragment 4-10
(ALA5, B-ALA8)-A-NEUROKININ*FRAGMENT 4-1 0
[ALA5, BETA-ALA8]-ALPHA-NEUROKININ FRAGMENT 4-10
alpha-neurokinin, fragment 4-10, [Ala5, beta-Ala8]
L-Methioninamide,L-α-aspartyl-L-alanyl-L-phenylalanyl-L-valyl-β-alanyl-L-leucyl-
L-Methioninamide, L-α-aspartyl-L-alanyl-L-phenylalanyl-L-valyl-β-alanyl-L-leucyl- (9CI)
3-amino-4-[[1-[[1-[[1-[[3-[[1-[(1-amino-4-methylsulfanyl-1-oxobutan-2-yl)amino]-4-methyl-1-oxopentan-2-yl]amino]-3-oxopropyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid | [Molecular Formula]
C35H56N8O9S | [MDL Number]
MFCD00133057 | [MOL File]
127633-71-0.mol | [Molecular Weight]
764.93 |
| Hazard Information | Back Directory | [Uses]
(β-Ala8)-Neurokinin A (4-10), a neuropeptide, is a potent and selective NK-2 tachykinin receptor (Neurokinin Receptor) agonist[1]. | [in vivo]
(β-Ala8)-Neurokinin A (4-10) (2 μg/kg; i.v.) increases colonic tone in conscious female dogs[2]. | [References]
[1] C A Maggi, et al. In vivo pharmacology of [beta Ala8]neurokinin A-(4-10), a selective NK-2 tachykinin receptor agonist. Eur J Pharmacol. 1990 Feb 20;177(1-2):81-6. DOI:10.1016/0014-2999(90)90552-h
[2] G Basilisco, et al. A selective NK-2 antagonist blocks the increase of canine colonic tone and ileal contractions induced by the NK-2 selective receptor agonist, [beta Ala8] neurokinin A-(4-10). Aliment Pharmacol Ther. 1994 Oct;8(5):527-33. DOI:10.1111/j.1365-2036.1994.tb00326.x |
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