| Identification | Back Directory | [Name]
Regramostim | [CAS]
127757-91-9 | [Synonyms]
CSF-2
MGI-1GM
Regramostim
Regramostime
Regramostimum
pluripoietin-
pluripoietin-a
GM-CSF from mouse
Regramostimum [inn-latin]
Regramostime [inn-french]
Human CSF2/GM-CSF Protein, Fc Tag
Human CSF2/GM-CSF Protein, His Tag
Recombinant Mouse GM-CSF/Csf2 Protein, No Tag
Recombinant Human GM-CSF/CSF2 Protein, No Tag
Recombinant Human GM-CSF/CSF2 Protein, His Tag
Recombinant Mouse GM-CSF/Csf2 Protein, His Tag
Colony-stimulating factor 2 (human clone pcsf-1 protein moiety reduced), glycoform gmc 89-107 |
| Hazard Information | Back Directory | [Uses]
Antineutropenic; hematopoietic stimulant. | [Uses]
GM-CSF (granulocyte-macrophage colony-stimulating factor) mouse has been used to check effect of GM-CSF on retinal ganglion cell neurite outgrowth in the retinal explants. | [General Description]
GM-CSF (granulocyte-macrophage colony-stimulating factor, also referred to as CSF2) is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. Recombinant murine GM-CSF is a 14.2kDa globular protein consisting of 124 amino acids residues. The human and murine molecules are species-specific and exhibit no cross-species reactivity. | [Biochem/physiol Actions]
GM-CSF (granulocyte-macrophage colony-stimulating factor, also referred to as CSF2) is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It enhances neutrophil migration. GM-CSF plays a crucial role in inflammatory and autoimmune diseases. In neutrophils, it promotes the expression of TLR2 (Toll-like receptor) and TLR2-associated interleukin 8 responses, thereby eliminating microbial attack. |
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| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
| Company Name: |
Biorbyt Ltd.
|
| Tel: |
+44 (0)1223 859 353 |
| Website: |
http://www.biorbyt.com |
|