| Identification | Back Directory | [Name]
5H-Pyrrolo[2,1-c][1,4]benzodiazepin-5-one, 1,2,3,11a-tetrahydro-7-methoxy-8-(phenylmethoxy)-, (11aS)- | [CAS]
127810-79-1 | [Synonyms]
5H-Pyrrolo[2,1-c][1,4]benzodiazepin-5-one, 1,2,3,11a-tetrahydro-7-methoxy-8-(phenylmethoxy)-, (11aS)- | [Molecular Formula]
C20H20N2O3 | [MOL File]
127810-79-1.mol | [Molecular Weight]
336.38 |
| Chemical Properties | Back Directory | [Melting point ]
58-61 °C | [Boiling point ]
570.8±50.0 °C(Predicted) | [density ]
1.26±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
3.76±0.20(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
Benzyl DC-81 (Compound 6a) is an anticancer agent with antiproliferative activity against A375 and MCF-7 cells[1]. | [References]
[1] Adiyala PR, et al. Development of pyrrolo[2,1-c][1,4]benzodiazepine β-glucoside prodrugs for selective therapy of cancer. Bioorg Chem. 2018 Feb;76:288-293. DOI:10.1016/j.bioorg.2017.12.002 |
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