| Identification | Back Directory | [Name]
Methyl tetrahydro-4H-pyran-4-one-3-carboxylate | [CAS]
127956-11-0 | [Synonyms]
methyl 4-oxooxane-3-carboxylate
Methyl 4-Oxotetrahydropyran-3-carboxylate
Methyl 4-oxotetrahydro-2H-pyran-3-carboxylate
Methyl 4-oxotetrahydro-1H-pyran-3-carboxylate
Methyl tetrahydro-4H-pyran-4-one-3-carboxylate
Methyl tetrahydro-4H-pyran-4-one-3-carboxylate-4
Methyl-4-oxotetrahydro-2h-pyran-3-carboxylic acid
4-Oxotetrahydropyran-3-carboxylic acid methyl ester
2H-Pyran-3-carboxylic acid, tetrahydro-4-oxo-, methyl ester | [Molecular Formula]
C7H10O4 | [MDL Number]
MFCD20921984 | [MOL File]
127956-11-0.mol | [Molecular Weight]
158.15 |
| Chemical Properties | Back Directory | [Boiling point ]
236.4±30.0 °C(Predicted) | [density ]
1.201±0.06 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [pka]
10.61±0.20(Predicted) | [Appearance]
Colorless to light yellow Liquid | [InChI]
InChI=1S/C7H10O4/c1-10-7(9)5-4-11-3-2-6(5)8/h5H,2-4H2,1H3 | [InChIKey]
SOWMVLQIMWETEK-UHFFFAOYSA-N | [SMILES]
C1OCCC(=O)C1C(OC)=O |
| Hazard Information | Back Directory | [Uses]
Methyl 4-oxotetrahydro-2H-pyran-3-carboxylate is a carboxylate derivative, and used as a pharmaceutical intermediate. | [Synthesis]
Methyl 4-oxotetrahydro-2H-pyran-3-carboxylate was synthesized by reacting tetrahydropyranone with dimethyl carbonate in the presence of TEA. | [References]
[1] Patent: WO2014/15291, 2014, A1. Location in patent: Page/Page column 183
[2] Patent: WO2016/210331, 2016, A1. Location in patent: Paragraph 0254; 0255
[3] Patent: WO2016/210330, 2016, A1. Location in patent: Paragraph 0520-0521
[4] Patent: WO2013/10092, 2013, A1. Location in patent: Page/Page column 26
[5] Patent: WO2013/12723, 2013, A1. Location in patent: Page/Page column 40 |
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