| Chemical Properties | Back Directory | [Boiling point ]
668.555±55.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.190±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
15.213±0.40(predicted) | [color ]
White to light brown |
| Hazard Information | Back Directory | [Uses]
CBD3063 is a selective modulator of collapsin response mediator protein 2 (CRMP2). CBD3063 uncouples Cav2.2 from CRMP2. CBD3063 reverses neuropathic and inflammatory pain by reducing membrane expression of CaV2.2[1][2]. | [References]
[1] Gomez K, et, al. A peptidomimetic modulator of the CaV2.2 N-type calcium channel for chronic pain. Proc Natl Acad Sci U S A. 2023 Nov 21;120(47):e2305215120. DOI:10.1073/pnas.2305215120
[2] Allen HN, et, al. Uncoupling the CRMP2-CaV2.2 Interaction Reduces Pain-Like Behavior in a Preclinical Joint-Pain Model. J Pain. 2024 Sep 2:104664. DOI:10.1016/j.jpain.2024.104664 |
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