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128113-19-9

128113-19-9 Structure

128113-19-9 Structure
IdentificationBack Directory
[Name]

C 1303
[CAS]

128113-19-9
[Synonyms]

C 1303
6H-[1,2,3]Triazolo[4,5,1-de]acridin-6-one, 5-[[2-(dimethylamino)ethyl]amino]-8-hydroxy-
[Molecular Formula]

C17H17N5O2
[MOL File]

128113-19-9.mol
[Molecular Weight]

323.35
Chemical PropertiesBack Directory
[Melting point ]

218-220 °C
[Boiling point ]

594.7±60.0 °C(Predicted)
[density ]

1.46±0.1 g/cm3(Predicted)
[pka]

7.38±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

NSC 645827 is an inhibitor for NAD(P)H: quinone oxidoreductase 1 (NQO1) with an IC50 of 0.7 μM[1].
[References]

[1] Jianwen Wang, et al. Identification and structure-guided development of triazole urea-based selective antagonists of Arabidopsis karrikin signaling. Nat Commun. 2025 Jan 2;16(1):104. DOI:10.1038/s41467-024-54801-1
[2] Chee S M. Design, Synthesis and Biological Evaluation of the Novel Inhibitors of Enzymes NQO1 and NQO2[M]. The University of Manchester (United Kingdom), 2014.
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